Thus, although infection initiates immune activation, dysregulated or persistent inflammation drives disease progression and severity
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Additionally, M2-like TAMs upregulate arginase 1 (Arg1), enhancing arginine metabolism and further depleting extracellular arginine, thereby exacerbating immunosuppression (93)
Tassavor, B
Stress and Metabolism DSIP protects against metabolic disruptions caused by stress by supporting mitochondrial oxidative phosphorylation ( 8, 9 )
[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Venkatakrishnan AJ, et al