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MgIG also downregulates the mRNA expression of TLR2, TLR4, and NF-B in the liver, thereby reducing the production of pro-inflammatory cytokines (e.g., TNF-, IL-6) and alleviating liver tissue inflammation and oxidative stress ( DG primarily alleviates amphotericin B-induced liver injury through dual mechanisms involving inhibition of oxidative stress and apoptosis (Zhao et al., 2022)

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