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Sixty-four male obese monkeys ( Macaca fascicularis , 823 years of age

GHK-Cu's evidence is genuinely supportive but methodologically weaker

Abbreviations AADAC: Arylacetamide deacetylase ALT: Alanine aminotransaminase APAP: Acetaminophen AST: Aspartate aminotransferase CCl 4 : Carbon tetrachloride CP: Ceruloplasmin DFO: Deferoxamine DILI: Drug-induced liver injury EDTA: Ethylenediamine- N , N , N , N -tetraacetic acid disodium ER: Endoplasmic reticulum Fer-1: Ferrostatin-1 GPX4: Glutathione peroxidase 4 HO1: Heme oxygenase 1 NQO1: NAD(P)H quinone oxidoreductase 1 MDA: Malondialdehyde MLM: Mouse liver microsomes MLS9: Mouse liver S9 fractions SDS: Sodium dodecyl sulfate SLC7A11: Solute carrier family 7 member 11 TBA: 2-Thioberbituric acid References Attia SM (2010) Deleterious effects of reactive metabolites

Second, it shifts melanin synthesis away from eumelanin (the darker brown-black pigment) toward phaeomelanin (a lighter yellow-pink pigment)

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