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Aboulmaouahib, S

Despite the substantial conformational dynamics when bound to AMY 3 R, Cagri maintains the bypass conformation across the motions, likely arising from the consistent TMD and linker interactions between RAMP3 and CTR that enable robust engagement of residues within the Cagri bypass motif

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It enhances biochemical signaling for collagen and glycosaminoglycan production, recruits immune and endothelial cells to injury sites, and promotes remodeling of connective tissue

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Curr Aging Sci