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First, PBMs increasingly negotiate exclusivity agreements with first-filer generic manufacturers during the 180-day window, agreeing to preferred formulary placement for the generic in exchange for pricing below WAC that is passed to the plan as savings

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These medications improve insulin resistance and related metabolic conditions, are increasingly used to support patients with autoimmune disease, reduce the risk of certain cardiovascular and neurologic conditions, and help manage chronic inflammation

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Some people come in for regular maintenance shots, while others start more frequently to rebuild low levels before spacing visits out