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Apoptotic cells typically upregulate the glycolytic pathway to provide additional energy, and mitochondria also participate in regulating apoptosis
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Drug-free NPs composed of selected anti-inflammatory nanomaterials, especially when functionalized with appropriate ligandscould reduce reliance on cytotoxic drugs and potentially mitigate long-term issues such as tolerance, escalating doses, and cumulative side effects [151]
Alongside their in vitro study, the Thomas Jefferson University-based research group also conducted a randomized trial in which patients were treated with either NAC for three months or received no treatment
Glutathione (GSH), a powerful antioxidant used in tissue preservation, has ferroptosis-regulating activity