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What the Research Says Several studies confirm that even mild dehydration may impair energy, mental performance, and physical endurance: A 2011 study found that just 1 } Explore More from This Series: The 4 Most Common Side Effects of GLP-1s And How to Manage Them Muscle Loss on GLP-1s

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Legitimate peptide therapies [like a GLP-1], intended for human use, require medical oversight, and must be dispensed through licensed pharmacies

3 Cardiac arrhythmias affected 2-11% of participants on retatrutide versus 2% on placebo, but none were serious

Proper site rotation minimizes these issues