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Capecitabine therapy has been shown to shift microbial taxa and enhance pathways for menaquinone (vitamin K) biosynthesis, which correlated with reduced chemotherapy-related toxicities, particularly peripheral sensory neuropathy (61)

It's contraindicated in patients with personal or family history of medullary thyroid carcinoma, causes gastrointestinal side effects in 3045% of users during titration, and requires ongoing prescriber oversight for dose adjustments

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Servono trial specificamente disegnati per la MASH per valutare leffettivo impatto epatico di retatrutide, tema ripreso nellarticolo Retatrutide e CagriSema: i nuovi farmaci anti-obesit che cambieranno la terapia

doi: 10.1523/JNEUROSCI.3588-08.2008 142 MohammadiM.NasehiM.ZarrindastM

Kopp et al