The neddylation level of NEDD4 increased both in vitro and in vivo (Fig
Histopathological analysis showed that the kidneys, brains, livers and lungs of mice in the positive control group had different degrees of damage, mainly manifested as congestion or edema
doi: 10.1016/j.canlet.2021.08.028
By boosting glutathione levels through injections, the bodys natural detoxification pathways are enhanced, potentially leading to improved overall health
Antioxidant enzymes such as superoxide dismutase 1 (SOD1), and glucose6phosphate dehydrogenase (G6PD) decrease from HMRD-induced oxidative stress (OxS) and protein degradation 50,51
Malik and Maqbool (2020) emphasized the need for biofortification of crops as a method necessary to achieve the above goal