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Employers need to approach GLP-1 coverage as a strategy decision, not just a coverage decision, so there are several key considerations at play, Williams said

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NSAIDs are known to cause gastric injury, and semaglutide delays stomach emptyinga mechanism that prolongs NSAID contact with the stomach lining

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4 Key points: Higher doses of Wegovy consistently produce greater average weight loss In STEP UP, 7.2 mg produced an average weight loss of 20.7%, compared with 17.5% on 2.4 mg Nearly half of the people on 7.2 mg lost at least 20% of their body weight Doses below 2.4 mg are generally considered titration steps, but many people can achieve significant weight loss on them, particularly if theyre combined with healthy lifestyle changes Going from no medication to 2.4 mg adds far more weight loss than going from 2.4 mg to 7.2 mg How weight loss changes with dose The science behind a higher dose Semaglutide mimics GLP-1, a hormone that communicates with the appetite centres in the brain and slows how quickly the stomach empties