Some patients reported nausea, leading Novo to reduce the dose, but efficacy was disappointing
482 Patients who receive HD may be at risk of the development of carnitine deficiency as a result of loss of carnitine during the dialysis procedure, in addition to possible reductions in dietary intake and endogenous synthesis
The full thermogenic and metabolic effects of glucagon receptor activation become most pronounced at 8 to 12 mg, which is typically reached by weeks 13 to 17
Assessing heterogeneity of treatment effect in real-world data
For best results, patients should maintain open communication with their healthcare provider about any side effects or concerns

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