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The second primary endpoint was added because, in EMPA-REG OUTCOME, there was greater benefit with respect to cardiovascular death and hospitalisation for heart failure than with respect to 3-point MACE

Even though this can be slightly uncomfortable and annoying, side effects are typically a good thingit means the vaccine is doing what its supposed to do

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FIGURE 5 The primary source of ROS in the endoplasmic reticulum is the formation of intramolecular disulfide bonds during the maturation of many secreted proteins and membrane proteins