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The alternating hypothesis suggests that cycling between a pure GLP-1 agonist and a dual GIP/GLP-1 agonist could prevent or delay this tolerance

As a GLP-1 analog, semaglutide supports hormonal regulation, improves insulin sensitivity, and drives HbA1c reduction in diabetes studies

India became one of the first major markets to see generic launches after Novo Nordisks core patent on the molecule expired there in March 2026

a BMI of 30 or higher)

This isnt a one-size-fits-all solution

Any use of GLP-1 agonists for binge eating disorder is off-label and should involve specialist oversight with continued psychological support