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Arzneimittelforschung 1992;42:1101-4

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however these variants explained only a small percentage of the genetic variation of the disorders, further supporting the concept that epigenetic processes play an important role [17]

Camptothecin (CPT) and its derivatives are known to target topoisomerase I (Top1) as their mechanism of action: did we miss something in CPT analogue molecular targets for treating human disease such as cancer

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