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The MHRA's Yellow Card scheme (yellowcard.mhra.gov.uk) has received some reports of anxiety-related symptoms with semaglutide products, though causality has not been definitively established

Peptide synthesis GIP and (Pro 3 )GIP were sequentially synthesised on an Applied Biosystems automated peptide synthesiser (model 432 A) using a standard solid-phase Fmoc procedure [28], starting from an Fmoc-Gln-Wang resin