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Interestingly, TAM were shown to secrete several pro-angiogenic cytokines and growth factors, such as VEGF (4446), MMP (4648), IL-10 (40, 46, 47, 49, 50), IL-8 (45, 46), FGF2 (45, 51, 52) and placental growth factor (PlGF) (52), allowing them to modulate angiogenic pathways

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Results Twenty-nine RCTs with a total of 26985 participants were recruited in the final analysis