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Loscalzo,Redox regulation of mitochondrial function.Antioxid Redox Signal, 2012

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doi: 10.1096/fj.202200634r 152 MaJ.ZhangZ.SuY.KangL.GengD.WangY.et al

Hypertension 39 , 184188 (2002)

Genetic variation in myeloperoxidase modifies the association of serum alpha-tocopherol with aggressive prostate cancer among current smokers

We assume that the oxidized C-terminal redox centre swings back to the conformation seen in the uncomplexed structures of TrxR1, thereby adopting the mentioned 'oxidized waiting position' again, completing the possible reaction cycle