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On the immune front, gut microbiota can increase systemic inflammation by releasing lipopolysaccharides (LPS) and proinflammatory cytokines, and they also produce amyloids, which may stimulate neural amyloid production via immune priming

This metaboloepigenetic rewiring is called metabostemness [80]

Contact for reagent and resource sharing Further information and requests for resources and reagents should be directed to and fulfilled by Se In Sung ([email protected]), Yun Sil Chang ([email protected]), and Ara Koh ([email protected])

Work to date concentrates on canonical pathways, leaving the core ferroptotic circuits, molecular targets and regulatory networks that drive retinal microvascular endothelial-cell (RMEC) injury undefined

Consequently, researchers observe more diverse responses across elasticity and matrix-related markers

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