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Instead, the body draws from both fat and muscle

For CrossFit athletes dealing with systemic inflammation from chronic high-intensity training, this has a compounding benefit -- it does not just help the specific injury, it reduces the overall inflammatory load that slows recovery across the board

Involvement of nuclear factor-kappa B (NF-B) in methotrexate-induced intestinal injury NF-kB is a key regulator of inflammation that is involved in the synthesis of inflammatory mediators and activation of pro-inflammatory cytokines (Liu et al