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Oxidative stress in DNA repeat expansion disorders: a focus on NRF2 signaling involvement
Hiu qu ty c a v ph thuc vic dng u n, chng nng y
Furthermore, both GLP-1 monotherapy and GLP-1MK-801 treatment resulted in decreased plasma triglyceride levels compared with the vehicle treatment (Fig
In line, Prx6 knockout mice exhibit markedly reduced levels of GPX4 and other selenoproteins, with this decrease being particularly pronounced in the brain [177] , highlighting the critical role of this redoxin in selenium metabolism and providing a missing link in selenoprotein biology that explains how cells coordinate thiol and selenium metabolism to counteract lipid peroxidation
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