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Approved Uses and Off-Label Considerations Ozempic is FDA-approved for specific indications, primarily focused on metabolic health

10.1016/j.biopha.2018.08.088 112 ShettyR.BasheerF

In addition, a large-scale clinical study demonstrated that GLP-1 analogues could reduce the mortality of patients with prostate cancer and diabetes (19)

Tirzepatide is a novel dual GLP-1 and glucose-dependent insulinotropic polypeptide receptor agonist recently approved for diabetes and weight loss

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Instead, addiction involves many systems, including gut sensory signaling, endocrine modulation, immune tone, microbiome-dependent stress regulation, and central reward circuitry