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Sermorelin is sometimes marketed for weight loss, but strong clinical studies have not shown meaningful benefits for obesity, visceral fat reduction, or GLP-1-related muscle preservation

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Its anti-wrinkle properties help to prevent and reduce the development of wrinkles, leaving the skin smooth and youthful

4,40 Insulin stimulation results in fatty acid synthesis in the adipose tissue, liver and lactating mammary glands, whilst simultaneously inhibiting lipolysis and fatty acid oxidation in the liver, skeletal muscle and adipose tissue

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Afamelanotide mostly hits MC1R and is FDA-approved for a rare skin condition called erythropoietic protoporphyria