Aidah Abu El Soud Alkaissi An-Najah National University Faculty of Nursing Paracetamol intoxicationAcetaminophen (N-acetyl-p-aminophenol) Defined as a peak plasma alanine aminotransferase (ALT) activity exceeding 1000 IU/L Aspartate transaminase (AST) exceeding 1000 IU/L indicates severe liver damage At risk of severe liver damage if he/she has ingested more than 150mg paracetamol/kg body weight, or, in adults, more than 12g (24 standard tablets) Dr
Protein damage tryptophan fluorescence (decrease in OD)
Heart disease, liver disease or kidney disease patients require medical supervision [47]
Lancet Psychiatry 5 (9), 739746
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Read more about NAC supplementation and glutathione levels in the research literature