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Han W, Zhang B, Zhao W, Zhao W, He J, Qiu X, Zhang L, Wang X, Wang Y, Lu H, Zhang Y, Xie Y, Geng Y, Zhao W, Huang Q, Zhang Y-W, Wang Z (2025) Ketogenic -hydroxybutyrate regulates -hydroxybutyrylation of TCA cycle-associated enzymes and attenuates disease-associated pathologies in Alzheimers mice

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Since the peptide is typically administered via subcutaneous injection, users may experience redness, swelling, or discomfort at the injection site

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Randomization was conducted using an interactive web response system, assigning participants in a 6:1 ratio to one of several treatment arms: once-weekly subcutaneous Cagrilintide administered in doses of 0.3, 0.6, 1.2, 2.4, or 4.5 mg, once-daily liraglutide 3.0 mg, or a volume-matched placebo