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N Engl J Med 2001

Eye symptoms if you have diabetes/retinopathy

Treat it like the drug that it is and only take it if necessary

Rather than forcing metabolic change through brute biochemical intervention, GLP-1 drugs supraphysiologically modulate endogenous signalling systems already evolved for energy regulation

This medications safety profile has not been studied in patients under the age of 18, pregnant and lactating people, or those with normal BMIs. At the time of publishing, the FDA has only approved three GLP-1 agonists for weight loss: Wegovy (semaglutide), Zepbound (tirzepatide), and Saxenda (liraglutide)

It means the relationship between concentration and results isn't linear