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Clinicians should specifically inquire about the nature, timing, and associated features of fatigue

The possible explanations for the higher insulin sensitivity in PWS could be the relatively lower visceral adipose tissue (VAT) and higher subcutaneous adipose tissue (SAT) than BMI-matched controls, as well as the predominant accumulation of subcutaneous fat in the trunk and proximal limbs, with a lower ratio of trunk-to-appendicular fat (167, 185, 186)

This decision could greatly affect the cases direction

However, subsequent studies identified endogenous GLP-1 as corresponding to the proglucagon fragment spanning amino acids 78 to 107

This brand-name form of semaglutide is not approved for treating diabetes

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