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The European Medicines Agencys 2025 synthetic peptide quality guideline treats peptide-related impurities as first-class critical quality attributes: deletion and truncated sequences, dimers, oligomers, and degradation products each need characterization, with European Pharmacopoeia practice pointing to reporting thresholds at 0.1% and identification thresholds above 0.5% for peptide-related impurities in pharmaceutical use
"But it is very preliminary." This "very important and exciting finding" could potentially provide "another treatment option for patients with chronic migraine, especially for those who did not previously respond to other current available treatments," said Dr
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