Oral semaglutide 50 mg performed better than placebo in reducing body weight and improving physical functioning and cardiometabolic risk factors, including waist circumference, blood pressure, lipids, and HbA1c, which could have contributed to reverting to normoglycaemia at week 68
That flexibility may improve convenience and long-term adherence for some patients
Reusing a syringe increases injection pain, infection risk, and the chance of contaminating your vial with bacteria from your skin
One storage trade-off: NaCl can speed aggregation in the vial over weeks. Mix smaller amounts and use within 12 weeks
[DOI] [PubMed] [Google Scholar] 62.Overgaard RV, Hertz CL, Ingwersen SH, Navarria A, Drucker DJ
Some people experience a brief weight plateau or small regain of 1-3 pounds during transition, which typically stabilizes within four to six weeks