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Except for 16S rRNA sequencing, all in vitro studies were based on at least three repeats and in vivo data on 510 mice per group with at least two independent repeats to achieve significant differences

Two-way analysis of variance (ANOVA) was used to analyze the statistical significance of the differences between multiple groups in terms of the time spent exploring each object during the training phase and testing phase in the NOR test, as well as the escape latency and escape distance in the MWM test

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