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Endogenous GLP-1 alters postprandial functional connectivity between homeostatic and reward-related brain regions involved in regulation of appetite in healthy lean males: a pilot study

Phase 2 dose-finding data The phase 2 trial tested cagrilintide at 0.3 mg, 0.6 mg, 1.2 mg, 2.4 mg, and 4.5 mg weekly

doi: 10.1271/bbb1961.39.387

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Pacing is an individualised approach that monitors energy expenditure to reduce the occurrence, duration, and severity of PEM (23)