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Being on any combination therapy early in the disease is associated with enduring advantages, sometimes termed "legacy effects," in which benefits lag behind for a while [39], [41]

The exception is severe nausea days when only liquids are tolerable.

OPTIONAL: If you tolerate heat, then you can do Sauna (10-30 minutes) or a warm/hot bath (10-30 minutes) or light exercise to sweat

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Taking oral semaglutide incorrectly can substantially reduce its effectiveness, whilst injectable formulations have varying requirements regarding meal timing

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