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No saturation behavior for GSSG was previously detected for the fusion construct between rxYFP and ScGrx1 31 , which makes sense considering that PfGrx and many other glutaredoxins are at least two orders of magnitude more active than ScGrx1 (Table 1) 14,56

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[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Oken B.S., Kaplan J., Klee D., Gallegos A.M

Whats clear is that by the early 2010s, the site was operational and growing, and by the time it shut down, it was being run by an estimated three to five employees generating revenue that dwarfed most licensed pharmaceutical operations