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Medications like Wegovy and Zepbound must be combined with intensive lifestyle changes, including a reduced-calorie diet and moderate exercise (150 minutes per week), and taken long-term to achieve significant and sustained weight loss
Making targeted changes to daily routines can support continued weight loss
Reduction of Liver Fat One of the most significant benefits of GLP-1 agonists in MASH treatment is their ability to reduce liver fat
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FUNDING: No funding was provided for this article
Liraglutide treatment increased the percentage of bihormonal insulin + glucagon + cells relative to the total number of insulin- and glucagon-expressing cells per islet in WT mice but not in KO mice (Figure 6, A and B
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