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This GLP-1 hormone binds to the G protein-coupled GLP-1 receptor (GLP-1R) and activates key intracellular metabolic pathways

Furthermore, the production of nucleotides supports the replenishment of the oxidized nucleotide pool and facilitates DNA repair

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This could be related to a compensatory increase in mtDNA expression in GCs to compensate for the ovarys lack of mitochondrial energy metabolism in order to adapt to the hypoxia in the follicular development microenvironment