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This results in chronic hypercortisolism, adrenocortical hyperplasia, glucose intolerance and mature-onset obesity, resembling human Cushings syndrome 64

10.1002/jnr.22217 74 UrsiniF.MaiorinoM.ValenteM.FerriL.GregolinC

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On the other hand, gastrointestinal disturbances are critical early indicators of severe thiamine deficiency causing pediatric Wernicke Encephalopathy (54)

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Lactoperoxidase: physicochemical properties, occurrence, mechanism of action and applications