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With retatrutide, Phase 2 trial data (Jastreboff et al., NEJM , 2023) demonstrated mean reductions in body weight of up to approximately 24% over 48 weeks at the highest dose studied

However, potential users in San Ramon should note that Retatrutide has not yet been submitted for FDA approval

The peptide's collagen-stimulating effects also complement vitamin C's antioxidant benefits when used in combination

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Whilst this is unlikely to cause problems in most patients who maintain a balanced diet, those with already compromised nutritional status or very restricted eating patterns should be monitored more closely

PMID 1685472