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The most commonly reported adverse events in Phase 2 and Phase 3 trials were gastrointestinal in nature, including nausea, diarrhea, vomiting, and constipation

They also found 47 lesions involving the adrenal cortex, pituitary, and testes

It provides potentially more effective method to fulfill the vitamin deficiencies in body against oral dosage form which needs to be passed through digestive system

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doi: 10.1210/en.2019-00074