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Neuroprotective effects of lixisenatide and liraglutide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinsons disease

Common overlapping side effects include gastrointestinal symptoms (nausea, vomiting, abdominal pain), increased heart rate and blood pressure, and excessive appetite suppression

Am J Clin Nutr 69(6):12021208 Esmarck B, Andersen JL, Olsen S, Richter EA, Mizuno M, Kjaer M (2001) Timing of postexercise protein intake is important for muscle hypertrophy with resistance training in elderly humans

This approach is medically reasonable, though some patients prefer the reassurance of baseline labs before starting any injectable medication

Ongoing clinical trials and future directions To definitively answer whether GLP modulation offers true disease-modifying benefits, the field must rely on ongoing prospective trials (93, 103, 110)