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Most attention has focused on the ascorbate-glutathione pathway, but several other candidate pathways may couple the availability of oxidants such as H 2 O 2 to changes in glutathione and thus impact on signaling pathways through regulation of protein thiol-disulfide status

Atomic structure of the entire mammalian mitochondrial complex I

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The conclusion of targeted genes studies is the plurality of dysregulated mechanisms as a cause or consequence of epigenetic modifications