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The NHS does not set an upper safe limit for B12 because harmful effects from excessive intake have not been definitively established

Contamination and purity concerns Without regulated manufacturing environments, contamination is always possible

Less common reports include fatigue 1224 hours after dosing, injection-site redness, and brief flushing

Anyone pregnant or nursing, anyone with a hormone-sensitive condition, and anyone on prescription diabetes or metabolic drugs falls outside what the research covers

Doctors don't routinely test for vitamin B12 levels, so vitamin B12 deficiency can go unnoticed