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The use of GLP-1, GIP, and dual/triple receptor agonists, as well as intranasal insulin, requires further evaluation in large clinical trials

Cardiometabolic outcomes have taken center stage, with clinical trials tracking secondary and composite endpoints beyond weight loss

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This is partly attributed to KPVs entry through colonic cells via PepT1 channels, which are significantly expressed in the intestine primarily during states of inflammation

The inflammation associated with acute pancreatitis is thought to damage nerve pathways controlling digestive function, particularly affecting the stomach muscles responsible for moving food to the small intestine

The survey demonstrated a link between increasing concomitant medication and the occurrence of adverse effects