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found that hypoglycemia was less common with liraglutide 3.0 mg than with placebo in individuals with overweight or obesity and insulin-treated type 2 diabetes [43]

Clinical trials comparing the two drugs directly are already underway at Eli Lilly, and that data will eventually inform switching protocols

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One option is a step-up approach, which may help ease people into treatment

Fig.2 Pleiotropic effects of GLP1-RA leading to improvement MASLD/MASH [2] GLP-1RA in MASH Treatment: Clinical Progress Several GLP-1RAs and related agents are currently in various phases of clinical development for MASH treatment [4]

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