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While oral DFP has a risk of hematological toxicity (Ruivard and Lobbes, 2023), oral DFX can cause hepatic and renal toxicity and gastrointestinal bleeding with chronic use (Yusuf et al., 2023)

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PET studies suggest a reduction in the 5-HT 2A receptor in the cortex in drug-nave patients (Perani et al., 2008)

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Immunotherapy may be held and/or discontinued based on the type and grade of endocrine irAE

Glutathione, often referred to as the "master antioxidant," plays a critical role in protecting cells from damage, promoting detoxification, and supporting a strong immune system