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Exp Mol Med 49 , e322, (2017)

& Wyatt, R

Compound-induced parasite growth inhibition was normalized to a no-drug control [0.5% (v/v) DMSO] and to a parasite growth inhibition positive control [50 M artemisinin (ART) and 50 M chloroquine (CQ) in 0.5% (v/v) DMSO], using the following formula: (ART CQ with (ART + &CQ) or (ART &CQ) 100

Most significantly, it prevents the production of melanin, which is the cause of skin discoloration and dark spots

doi:10.1016/j.explore.2021.09.006 Pakowska-Godzik E, Lachowicz K, Rosoowska-Huszcz D

However, it has to be kept in mind that there is an interplay between DNA methylation and chromatin configuration, which is regulated by more processes than just DNMTs