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2003 The landmark 2003 study by Molinoff, Shadiack, Earle, Diamond, and Quon published in Annals of the New York Academy of Sciences confirmed that PT-141 administration to normal men and patients with erectile dysfunction produced a rapid, dose-dependent increase in erectile activity establishing the foundational clinical pharmacodynamic data for PT-141s erectile research application and confirming that the CNS melanocortin pathway generates erectile responses independently of peripheral vascular mechanisms

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A compound that produces identical protective effects whether administered systemically or topically to the target tissue suggests both a circulating effector mechanism and a local tissue-level mechanism, consistent with the dual NO-VEGF angiogenic pathway described above

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He has a great demeanor that shows he really cares about his patients