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It creates a high risk of contamination that can lead to skewed data or failed experiments

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Strand TA, Taneja S, Kumar T, et al

Unlike other treatments injected into the veins, B12 shots are administered into the muscles to avoid losing a huge amount when the person passes urine

[1] Retatrutide: What the Evidence Actually Shows Retatrutides pivotal obesity dataset is a Phase 2, double-blind, randomised, placebo-controlled trial in adults with obesity (or overweight plus a weight-related condition), testing once-weekly doses up to 12 mg over 48 weeks