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In addition to its role in cancer cells, -KG supports the self-renewal of naive murine embryonic stem cells (mESCs) by promoting histone and DNA demethylation 104

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L., Tsyganok T

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Rare but serious side effects include pancreatitis, gallbladder disease, and the theoretical risk of thyroid C-cell tumors seen in animal studies (not confirmed in humans at therapeutic doses)

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Skin barrier function in psoriasis and atopic dermatitis: Transepidermal water loss and temperature as useful tools to assess disease severity

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These could trigger an insulin response

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For the most up-to-date criteria, refer to the relevant NICE technology appraisals or speak to your GP

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