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Key timeline for Eli Lillys orforglipron: The approval of the first oral GLP-1 pill for weight loss expands the treatment landscape for obesity

Up to 30% of patients experience side effects that include fluid retention, joint and muscle pain, carpal tunnel syndrome (pressure on the nerve in the wrist causing hand pain and numbness), and high blood sugar levels

Add a small amount of lukewarm water to your hands and massage again to emulsify the oil into a milky consistency

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GLP-1 users may differ from nonusers in ways that are not fully captured, such as socioeconomic status, health behaviors, disease severity, medication adherence, or access to care." Lakkis notes that the study also did not report how much weight participants lost, making it difficult to determine how much of the benefit may have been driven by weight reduction itself

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