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Introduction We focused on the stable gastric pentadecapeptide BPC 157 ( Thus, we suggest that one single application of the NO-synthase (NOS) blocker N(G)-nitro-L-arginine methyl ester (L-NAME) may induce retinal ischemia in rats, and that the stable pentadecapeptide BPC 157 may be the therapy, since it may interact with the NO-system and may counteract various adverse effects of L-NAME application (see In the previous eye research studies, BPC 157 counteracts atropine-mydriasis, but it also opposes an immediate and hour-lasting miotic effect of L-NAME in rats and guinea pigs, and participates in pupil control potentially via NO-mediated and cholinergic mechanisms ( This may be essential for the effective counteraction of the damaging effect of the retrobulbar L-NAME application

GSH is a tripeptide that can directly neutralize free radicals and regenerate other antioxidants, maintaining the balance of oxidative stress within cells [15]

CNS Neurosci Ther (2019) 25:46575

Supplements and Over-the-Counter Products Berberine Like metformin, berberine activates AMPK

Glucomannan is a natural fibre widely used in glucomannan weight management supplements in the UK to support appetite control

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