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1996;271:C142437

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Over time, the duration and frequency of these flares may increase, resulting in chronic gouty arthritis and subcutaneous deposits of crystals, referred to as tophi, both of which can lead to the destruction of joints and musculoskeletal disability

*2: Highest concentration by Quality First standards

Impaired Activity of the -Glutamyl Cycle in Nephropathic Cystinosis Fibroblasts